Description

5-Bromo-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid is a high-value brominated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents, enabling the exploration of new therapeutic and pesticidal pathways. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology: Employed as a molecular probe or scaffold in drug discovery and target identification studies.
• Material Science: Potential precursor for advanced organic electronic materials and ligands in catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-Bromo-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid
CAS No.	916325-85-4
Molecular Formula	C7H4BrN3O2
Molecular Weight	242.03 g/mol
Synonyms	5-Bromo-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; 5-Bromo-3-carboxy-1H-pyrazolo[3,4-b]pyridine; 5-Bromo-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; 916325-85-4; 5-Bromo-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; 5-Bromo-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; 5-Bromo-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.