Description

2-Aminomethyl-5-Bromo-Phenol Hydrochloride is a high-purity, halogenated phenolic amine salt with significant synthetic utility. This compound serves as a versatile and valuable pharmaceutical intermediate and organic building block for the development of novel active molecules. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators that require brominated phenolic structures.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis and coordination chemistry research.
• Material Science Research: Intermediate for synthesizing functional polymers, dyes, and advanced organic materials.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and diagnostic agents in biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	2-Aminomethyl-5-Bromo-Phenol Hydrochloride
CAS No.	916213-66-6
Molecular Formula	C7H9BrClNO
Molecular Weight	238.51 g/mol
Synonyms	5-Bromo-2-(aminomethyl)phenol hydrochloride; (5-Bromo-2-hydroxybenzyl)amine hydrochloride; 2-(Aminomethyl)-5-bromophenol HCl; 5-Bromo-2-hydroxybenzylamine hydrochloride; 2-Amino-6-bromobenzyl alcohol hydrochloride (tautomeric form); 5-Bromosalicylamine hydrochloride; 2-Hydroxy-5-bromobenzylamine hydrochloride; 5-Bromo-2-(aminomethyl)phenol monohydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Aminomethyl-5-Bromo-Phenol Hydrochloride is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant analytical techniques. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.