Description

2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its benzo-fused oxazine core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities in medicinal chemistry research. It is primarily sought after by R&D laboratories and manufacturing facilities in the pharmaceutical, agrochemical, and fine chemical sectors for its role as a versatile building block.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for the design and development of new chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides.
• Fine Chemical Production: Employed as a specialized building block for synthesizing dyes, pigments, and other performance chemicals.
• Academic & Industrial R&D: A valuable reagent for organic synthesis methodologies and the exploration of novel heterocyclic compounds.

Basic Information

Product Name	2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carbonitrile
CAS No.	916210-01-0
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	2-Methyl-3-oxo-4H-1,4-benzoxazine-6-carbonitrile; 6-Cyano-2-methyl-4H-3,1-benzoxazin-4-one; 2-Methyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazine-6-carbonitrile; 2-Methyl-4H-benzo[b][1,4]oxazin-4-one-6-carbonitrile; 916210-01-0; Benzo[b][1,4]oxazine-6-carbonitrile, 3,4-dihydro-2-methyl-3-oxo-; 2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.