Description

n-(3-Amino-4-Chlorophenyl)Cyclobutanecarboxamide CAS NO 916052-80-7 is a specialized organic compound featuring a cyclobutane carboxamide core linked to a substituted aniline moiety. This unique structure makes it a valuable pharmaceutical intermediate and research chemical for the synthesis of novel active molecules. It is primarily sought by pharmaceutical R&D and fine chemical synthesis sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in oncology and CNS research.
• Agrochemical Research: Used in the development of novel herbicides and pesticides due to its chlorinated aromatic structure.
• Material Science: Serves as a monomer or precursor for advanced polymers and specialty materials.
• Organic Synthesis: A versatile reagent for constructing complex molecules in academic and industrial laboratories.
• Bioconjugation: The amino group allows for coupling reactions in the development of biochemical probes.

Basic Information

Item	Details
Product Name	n-(3-Amino-4-Chlorophenyl)Cyclobutanecarboxamide
CAS No.	916052-80-7
Molecular Formula	C11H13ClN2O
Molecular Weight	224.69 g/mol
Synonyms	3-Amino-4-chloro-N-cyclobutylbenzamide; Cyclobutanecarboxamide, N-(3-amino-4-chlorophenyl)-; 4-Chloro-3-aminophenyl cyclobutyl ketone amine; N-(3-Amino-4-chlorophenyl)cyclobutanecarboxamide; 916052-80-7; 3-Amino-4-chlorobenzoylcyclobutylamine; 4-Chloro-m-phenylenediamine, N-cyclobutanoyl derivative
EINECS	Contact for details

Quality Control

Our n-(3-Amino-4-Chlorophenyl)Cyclobutanecarboxamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.