Description

(R)-2-(2-Acetylphenyl)-2-Hydroxyacetic Acid is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways in university and corporate laboratories.

Basic Information

Product Name	(R)-2-(2-Acetylphenyl)-2-Hydroxyacetic Acid
CAS No.	915971-32-3
Molecular Formula	C10H10O4
Molecular Weight	194.18 g/mol
Synonyms	(R)-2-Hydroxy-2-(2-acetylphenyl)acetic acid; (R)-2-(2-Acetylphenyl)-2-hydroxyethanoic acid; (R)-Mandelic acid, 2'-acetyl-; (R)-O-Acetylmandelic acid (specific isomer); (2R)-2-Hydroxy-2-(2-acetylphenyl)acetic acid; (R)-α-Hydroxy-2-acetylbenzeneacetic acid; (R)-2-Acetylphenylglycolic acid
EINECS	Contact for details

Quality Control

Our (R)-2-(2-Acetylphenyl)-2-Hydroxyacetic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.