Description

3-Cyano-4-(3-Chloro-4-Fluoroanilino)-7-Ethoxy-6-(Phthalimidyl)Quinoline is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in the creation of targeted kinase inhibitors. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based kinase inhibitor candidates.
• Oncology Drug Discovery: Used in R&D for developing targeted therapies against specific cancer pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Integral in multi-step synthetic routes for producing high-value active pharmaceutical ingredients.
• Biochemical Research: Employed in the development of assay tools and probes for studying enzyme kinetics and cellular signaling.

Basic Information

Product Name	3-Cyano-4-(3-Chloro-4-Fluoroanilino)-7-Ethoxy-6-(Phthalimidyl)Quinoline
CAS No.	915945-40-3
Molecular Formula	C26H15ClFN5O3
Molecular Weight	499.88 g/mol
Synonyms	3-Cyano-4-(3-chloro-4-fluoroanilino)-7-ethoxy-6-(phthalimidyl)quinoline; 6-(1,3-Dioxoisoindolin-2-yl)-7-ethoxy-4-[(3-chloro-4-fluorophenyl)amino]quinoline-3-carbonitrile; 915945-40-3; Quinoline derivative CAS 915945-40-3; 4-[(3-Chloro-4-fluorophenyl)amino]-6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-7-ethoxy-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Cyano-4-(3-Chloro-4-Fluoroanilino)-7-Ethoxy-6-(Phthalimidyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable local and international regulations for industrial chemicals.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.