Description

[2-(2-Bromo-Phenyl)-Ethyl]-(1,1-Dioxo-Tetrahydrothiophen-3-Yl)-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily sought after by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the creation of new drug candidates, particularly in areas requiring sophisticated heterocyclic and sulfonamide-based structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates and new chemical entities (NCEs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with targeted biological activity.
• API Synthesis: Serves as a key building block for the commercial-scale production of active pharmaceutical ingredients, especially those containing bromophenyl and sulfone functional groups.
• Process Development: Employed in route scouting and scale-up studies to establish efficient and cost-effective manufacturing processes for complex molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	[2-(2-Bromo-Phenyl)-Ethyl]-(1,1-Dioxo-Tetrahydrothiophen-3-Yl)-Amine Hydrochloride
CAS No.	915402-21-0
Molecular Formula	C₁₂H₁₅BrClNO₂S
Molecular Weight	352.67 g/mol
Synonyms	N-[2-(2-Bromophenyl)ethyl]-1,1-dioxotetrahydro-3-thiophenamine hydrochloride; 3-[[2-(2-Bromophenyl)ethyl]amino]thiolane 1,1-dioxide hydrochloride; 2-(2-Bromophenyl)-N-(1,1-dioxothiolan-3-yl)ethanamine hydrochloride; Tetrahydro-3-[[2-(2-bromophenyl)ethyl]amino]thiophene 1,1-dioxide hydrochloride; (2-(2-Bromophenyl)ethyl)(1,1-dioxotetrahydrothiophen-3-yl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our [2-(2-Bromo-Phenyl)-Ethyl]-(1,1-Dioxo-Tetrahydrothiophen-3-Yl)-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.