Description

4,8-Dichloro-6-Nitro-Quinoline-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring halogen, nitro, and nitrile substituents, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Serves as a critical building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient quinoline core.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via reactions at the chloro, nitro, and nitrile groups, enabling library synthesis for high-throughput screening.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized quinoline-derived dyes and colorants.

Basic Information

Product Name	4,8-Dichloro-6-Nitro-Quinoline-3-Carbonitrile
CAS No.	915369-46-9
Molecular Formula	C10H3Cl2N3O2
Molecular Weight	268.05 g/mol
Synonyms	4,8-Dichloro-6-nitroquinoline-3-carbonitrile; 3-Cyano-4,8-dichloro-6-nitroquinoline; 6-Nitro-4,8-dichloroquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 4,8-dichloro-6-nitro-; 915369-46-9; 4,8-Dichloro-6-nitro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4,8-Dichloro-6-Nitro-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.