Description

3-Quinolinecarbonitrile, 6-Amino-8-Chloro-4-[(3-Chloro-4-Fluorophenyl)Amino]- is a high-purity, multi-functional heterocyclic organic compound designed for advanced chemical synthesis. This molecule matters as a critical pharmaceutical intermediate, offering a versatile scaffold for developing novel active ingredients. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and targeted therapy research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its complex quinoline and aniline structure for biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor or core structure in the synthesis of electron-transport or host materials for advanced display technologies.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized nitrogen-containing ligands for transition metal catalysis in asymmetric synthesis.
• Fluorescent Probe Development: Utilized as a base structure for creating sensitive and selective fluorescent probes or sensors for biological and chemical detection.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	3-Quinolinecarbonitrile, 6-Amino-8-Chloro-4-[(3-Chloro-4-Fluorophenyl)Amino]-
CAS No.	915364-18-0
Molecular Formula	C₁₆H₉Cl₂FN₄
Molecular Weight	363.17 g/mol
Synonyms	6-Amino-8-chloro-4-[(3-chloro-4-fluorophenyl)amino]quinoline-3-carbonitrile; 4-[(3-Chloro-4-fluorophenyl)amino]-6-amino-8-chloroquinoline-3-carbonitrile; 8-Chloro-6-amino-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile; 915364-18-0; 6-Amino-8-chloro-4-(3-chloro-4-fluoroanilino)quinoline-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarbonitrile, 6-Amino-8-Chloro-4-[(3-Chloro-4-Fluorophenyl)Amino]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; therefore, handling under an inert atmosphere is recommended for long-term storage or when working with large quantities. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.