Description

5-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-2-Hydroxybenzoic Acid is a specialized, high-purity chemical building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular assembly, particularly in the development of novel pharmaceutical intermediates and complex organic materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Synthesis & Modification: Used in solid-phase peptide synthesis (SPPS) for the introduction of specific functional groups or as a protected amino acid derivative.
• Linker Chemistry: Serves as a versatile linker or spacer molecule in bioconjugation and the development of antibody-drug conjugates (ADCs).
• Protecting Group Strategy: The Fmoc (9-fluorenylmethoxycarbonyl) moiety is integral for temporary amine protection in multi-step organic syntheses.
• Research & Development: Essential for academic and industrial research in medicinal chemistry, chemical biology, and material science.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke organic molecules and fine chemicals.

Basic Information

Product Name	5-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-2-Hydroxybenzoic Acid
CAS No.	915282-95-0
Molecular Formula	C22H17NO5
Molecular Weight	375.37 g/mol
Synonyms	5-[(Fmoc-amino)]salicylic acid; 5-(Fmoc-amino)-2-hydroxybenzoic acid; 2-Hydroxy-5-[(9H-fluoren-9-ylmethoxy)carbonylamino]benzoic acid; Fmoc-5-Aminosalicylic Acid; 5-Amino-2-hydroxybenzoic acid Fmoc derivative; N-Fmoc-5-aminosalicylic acid; 5-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-hydroxybenzoic acid
EINECS	Contact for details

Quality Control

Our 5-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-2-Hydroxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.