Description

4-(1-Azetidine Carbonyl)-Benzoic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 915199-15-4. This compound is a key building block in modern medicinal chemistry, valued for its unique azetidine moiety which is crucial for modulating the pharmacokinetic and pharmacodynamic properties of target molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents, particularly in areas like enzyme inhibition and receptor modulation.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Protease Inhibitor Development: Used in research and production of inhibitors for proteolytic enzymes involved in numerous physiological and pathological processes.
• Kinase Inhibitor Synthesis: Serves as a core scaffold or side-chain component in the creation of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology & Probe Development: Employed in the design of chemical probes for studying protein function and identifying new drug targets within cellular systems.
• Peptidomimetic Chemistry: Integral for constructing peptidomimetic compounds that mimic natural peptides but with enhanced stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	4-(1-Azetidine Carbonyl)-Benzoic Acid
CAS No.	915199-15-4
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	4-(Azetidine-1-carbonyl)benzoic acid; 4-(1-Azetidinylcarbonyl)benzoic Acid; Benzoic acid, 4-(1-azetidinylcarbonyl)-; 4-Carboxybenzoylazetidine; Azetidine-1-carboxylic acid, 4-benzoyl-; 915199-15-4; 4-(Azetidine-1-carbonyl)-benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(1-Azetidine Carbonyl)-Benzoic Acid is manufactured and tested under a strict quality management system. We provide material that meets high-purity standards suitable for research and pharmaceutical development. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation upon exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.