Description

5-Bromo-2-Cyanonicotinic Acid is a versatile and high-value brominated heterocyclic building block essential for modern synthetic chemistry. This compound matters for its role as a key precursor in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research institutions and industrial manufacturers developing active pharmaceutical ingredients (APIs), advanced materials, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its functional groups for structural diversification.
• Material Science: Serves as a precursor for creating functionalized organic materials and liquid crystals.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the bromo-cyano-pyridine moiety into more complex architectures.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	5-Bromo-2-Cyanonicotinic Acid
CAS No.	914637-97-1
Molecular Formula	C7H3BrN2O2
Molecular Weight	227.02 g/mol
Synonyms	5-Bromo-2-cyanopyridine-3-carboxylic Acid; 3-Carboxy-5-bromo-2-cyanopyridine; 2-Cyano-5-bromonicotinic Acid; 5-Bromo-2-cyano-3-pyridinecarboxylic Acid; 914637-97-1; 5-Br-2-CN-nicotinic Acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Cyanonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.