Description

2-Benzenesulfonyl-5-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional organic intermediate characterized by its distinct benzenesulfonyl and trifluoromethyl substituents. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for designing novel polymers, liquid crystals, or organic electronic materials with specific sulfone-based properties.
• Chemical Biology & Proteomics: Potential use as a building block for activity-based probes or protein labeling reagents due to its reactive carboxylic acid and sulfone moieties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	2-Benzenesulfonyl-5-(Trifluoromethyl)Benzoic Acid
CAS No.	914637-55-1
Molecular Formula	C14H9F3O4S
Molecular Weight	330.28 g/mol
Synonyms	5-(Trifluoromethyl)-2-(phenylsulfonyl)benzoic acid; [5-(Trifluoromethyl)-2-(phenylsulfonyl)]benzoic Acid; 2-(Benzenesulfonyl)-5-(trifluoromethyl)benzoic Acid; Benzoic acid, 2-(phenylsulfonyl)-5-(trifluoromethyl)-; 2-(Phenylsulfonyl)-5-(trifluoromethyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Benzenesulfonyl-5-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets precise customer specifications and high industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.