Description

3-n-Boc-Aminomethyl-Benzylamine Hcl is a protected amine derivative, specifically a benzylamine compound featuring a tert-butoxycarbonyl (Boc) protecting group on the aminomethyl side chain. This high-purity building block is critical for ensuring the integrity and yield of complex synthetic sequences, particularly in peptide and small molecule drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Peptide Synthesis: Used for the controlled introduction of benzylamine moieties into peptide chains while protecting reactive amine functionalities.
• Protecting Group Chemistry: Serves as a reagent where the Boc group is required for selective protection and subsequent deprotection strategies.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or molecular recognition studies.
• Bioconjugation: Useful in linker chemistry for attaching molecules to biomolecules, proteins, or surfaces.
• Chemical Biology Research: Applied in the synthesis of probes and tool compounds for studying biological pathways.

Basic Information

Product Name	3-n-Boc-Aminomethyl-Benzylamine Hcl
CAS No.	914465-97-7
Molecular Formula	C14H22N2O2 • HCl
Molecular Weight	286.80 g/mol
Synonyms	1-(3-(((tert-Butoxycarbonyl)amino)methyl)phenyl)methanamine hydrochloride; 3-((Boc-amino)methyl)benzylamine hydrochloride; tert-Butyl N-[(3-(aminomethyl)phenyl)methyl]carbamate hydrochloride; 3-(Aminomethyl)benzylcarbamic acid tert-butyl ester hydrochloride; 3-((tert-Butoxycarbonylamino)methyl)benzylamine HCl; (3-(Aminomethyl)phenyl)methyl-carbamic acid tert-butyl ester hydrochloride; Boc-AMBn HCl
EINECS	Contact for details

Quality Control

Our 3-n-Boc-Aminomethyl-Benzylamine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.