Description

1-[4-(2,2-Dichlorocyclopropyl)Phenyl]-2-(Phenylsulfonyl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique dichlorocyclopropyl and phenylsulfonyl functional groups. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates with complex cyclic structures.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides, leveraging its reactive dichlorocyclopropyl moiety.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic applications.
• Process Chemistry: Employed in route scouting and scale-up studies for the efficient manufacturing of target molecules.
• Custom Synthesis Building Block: Provided to fine chemical companies for the bespoke synthesis of client-specific compounds for various R&D programs.

Basic Information

Product Name	1-[4-(2,2-Dichlorocyclopropyl)Phenyl]-2-(Phenylsulfonyl)Ethanone
CAS No.	914357-57-6
Molecular Formula	C17H14Cl2O3S
Molecular Weight	369.26 g/mol
Synonyms	2,2-Dichloro-1-[4-(2-phenylethanesulfonyl)phenyl]cyclopropane; 1-[4-(2,2-Dichlorocyclopropyl)phenyl]-2-(phenylsulfonyl)ethan-1-one; 2-(Phenylsulfonyl)-1-[4-(2,2-dichlorocyclopropyl)phenyl]ethanone; 914357-57-6; Ethanone, 1-[4-(2,2-dichlorocyclopropyl)phenyl]-2-(phenylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 1-[4-(2,2-Dichlorocyclopropyl)Phenyl]-2-(Phenylsulfonyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.