Description

(5-Bromopyrazin-2-Yl)Carbamic Acid tert-Butyl Ester is a high-purity, protected heterocyclic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive pyrazine scaffold with orthogonal protecting groups, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology: Used in the design and synthesis of molecular probes and tool compounds for target identification and validation.
• Material Science: Potential monomer or precursor for creating functionalized polymers and advanced organic materials.
• Cross-Coupling Reactions: The bromine substituent makes it a valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Medicinal Chemistry: Core structure for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.

Basic Information

Product Name	(5-Bromopyrazin-2-Yl)Carbamic Acid tert-Butyl Ester
CAS No.	914349-79-4
Molecular Formula	C9H12BrN3O2
Molecular Weight	274.12 g/mol
Synonyms	tert-Butyl (5-bromopyrazin-2-yl)carbamate; N-Boc-2-amino-5-bromopyrazine; 5-Bromo-2-((tert-butoxycarbonyl)amino)pyrazine; 2-Amino-5-bromopyrazine, N-Boc protected; Boc-5-Bromo-2-aminopyrazine; (5-Bromo-2-pyrazinyl)carbamic acid 1,1-dimethylethyl ester; 5-Bromo-2-pyrazinamine, N-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our (5-Bromopyrazin-2-Yl)Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.