Description

3-Amino-2-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a fluorine substituent, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, pesticides, and fungicides with enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Material Science Research: Intermediate for synthesizing fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and fluorescent tags for biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Item	Detail
Product Name	3-Amino-2-Fluorobenzoic Acid
CAS No.	914223-43-1
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	2-Fluoro-3-aminobenzoic acid; Benzoic acid, 3-amino-2-fluoro-; 3-Amino-2-fluorobenzoic acid; 2-Fluoro-m-aminobenzoic acid; 3-Amino-2-fluoro-benzoic acid; 2-Fluoro-3-aminobenzoic acid; 3-Amino-2-fluorobenzoic acid CAS 914223-43-1
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Fluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	198°C - 202°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.