Description

3-Bromo-2-Chloromethyl-Benzoic Acidmethyl Ester is a high-purity organic building block essential for advanced chemical synthesis. This compound is valued for its dual reactive sites, the bromo and chloromethyl groups, which enable selective functionalization and the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with benzofused ring systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to create complex organic molecules.
• Ligand and Catalyst Development: Useful for constructing novel chelating ligands for metal catalysts used in asymmetric synthesis.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and organic pigments.

Basic Information

Product Name	3-Bromo-2-Chloromethyl-Benzoic Acidmethyl Ester
CAS No.	914220-72-7
Molecular Formula	C10H10BrClO2
Molecular Weight	277.54 g/mol
Synonyms	Methyl 3-Bromo-2-(chloromethyl)benzoate; Benzoic acid, 3-bromo-2-(chloromethyl)-, methyl ester; 2-Chloromethyl-3-bromobenzoic acid methyl ester; Methyl 2-chloromethyl-3-bromobenzoate; 3-Bromo-2-chloromethyl methyl benzoate; 914220-72-7; Methyl 3-bromo-2-chloromethylbenzoate
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloromethyl-Benzoic Acidmethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are sealed under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.