Description

8-Bromoquinoline-2-Carboxylic Acid is a high-purity, versatile brominated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated quinoline structure makes it an essential precursor for developing novel pharmaceuticals, agrochemicals, and functional materials. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and fine chemical industries seeking to create complex molecules with specific biological or chemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of quinoline-based drug candidates with potential antimicrobial, anticancer, or anti-inflammatory properties.
• Agrochemical Research: Used in the discovery and synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLEDs or conductive polymers, where the bromine atom facilitates further functionalization via cross-coupling reactions.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying biological processes and target identification.
• Academic and R&D Laboratories: A fundamental reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	8-Bromoquinoline-2-Carboxylic Acid
CAS No.	914208-15-4
Molecular Formula	C₁₀H₆BrNO₂
Molecular Weight	252.07 g/mol
Synonyms	8-Bromoquinoline-2-carboxylic acid; 2-Quinolinecarboxylic acid, 8-bromo-; 8-Bromo-2-quinolinecarboxylic acid; 8-Bromoquinaldinic acid; 8-Bromoquinoline-2-carboxylate; 914208-15-4; 8-Br-quinoline-2-COOH
EINECS	Contact for details

Quality Control

Our 8-Bromoquinoline-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry standards and can support development projects requiring specific analytical protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.