Description

8-Fluoroquinoline-2-Carboxylic Acid is a high-purity fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which introduces both a carboxylic acid handle and a fluorine atom onto the quinoline scaffold, enabling precise modifications for developing novel active compounds. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs) targeting bacterial infections.
• Agrochemical Research: Used in developing new generations of herbicides and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, ligands, and organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Biochemical Tool Development: Utilized in the design and synthesis of fluorescent probes, enzyme inhibitors, and other research tools for biological studies.

Basic Information

Product Name	8-Fluoroquinoline-2-Carboxylic Acid
CAS No.	914208-13-2
Molecular Formula	C₁₀H₆FNO₂
Molecular Weight	191.16 g/mol
Synonyms	8-Fluoro-2-quinolinecarboxylic acid; 2-Quinolinecarboxylic acid, 8-fluoro-; 8-Fluoroquinoline-2-carboxylic acid; 8-Fluoroquinaldic acid; 914208-13-2; 8-Fluoro-2-quinaldic acid
EINECS	Contact for details

Quality Control

Our 8-Fluoroquinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our commitment is to deliver material of consistent high purity and reliable performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.