Description

1H-Indole-1,3-Dicarboxylic Acid, 4-Bromo-, 1-(1,1-Dimethylethyl)Ester CAS NO 914203-00-2 is a high-purity, brominated indole derivative that serves as a critical advanced pharmaceutical intermediate and custom synthesis building block. Its unique molecular structure makes it invaluable for constructing complex heterocyclic frameworks in medicinal chemistry. This compound is primarily sought by R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel indole-based drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides with specific modes of action.
• Material Science: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions and heterocycle functionalization.
• Custom Synthesis & Scale-Up: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for process development and pilot-scale production of proprietary compounds.

Basic Information

Product Name	1H-Indole-1,3-Dicarboxylic Acid, 4-Bromo-, 1-(1,1-Dimethylethyl)Ester
CAS No.	914203-00-2
Molecular Formula	C15H16BrNO4
Molecular Weight	354.20 g/mol
Synonyms	4-Bromo-1-(tert-butoxycarbonyl)-1H-indole-3-carboxylic acid; 1-(tert-Butyl) 4-bromo-1H-indole-1,3-dicarboxylate; 4-Bromo-1H-indole-1,3-dicarboxylic acid 1-(1,1-dimethylethyl) ester; tert-Butyl 4-bromo-1H-indole-1,3-dicarboxylate; 4-Bromo-1-Boc-indole-3-carboxylic acid; Boc-4-Br-indole-3-COOH; 914203-00-2; 4-Bromo-1-(tert-butoxycarbonyl)indole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of our 1H-Indole-1,3-Dicarboxylic Acid, 4-Bromo-, 1-(1,1-Dimethylethyl)Ester is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.