Description

(R)-1,3'-Bipyrrolidine Dihydrochloride is a high-purity, chiral diamine building block and salt form of significant value in advanced organic synthesis. Its primary importance lies in its role as a key intermediate for constructing complex molecules with specific three-dimensional configurations, which is critical for developing active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for asymmetric synthesis and catalysis.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting neurological and metabolic disorders.
• Asymmetric Catalyst Ligand Precursor: Used to develop and synthesize novel chiral ligands for transition metal catalysis, enabling enantioselective C-C and C-N bond-forming reactions.
• Agrochemical Synthesis: Serves as a key intermediate in the production of enantiomerically pure pesticides and herbicides, where specific stereochemistry can impact biological activity and environmental profile.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Peptidomimetic Scaffold: The bipyrrolidine structure is valuable for creating conformationally restricted peptide analogs and protease inhibitors.

Basic Information

Product Name	(R)-1,3'-Bipyrrolidine Dihydrochloride
CAS No.	913702-34-8
Molecular Formula	C8H18N2·2HCl
Molecular Weight	223.16 g/mol
Synonyms	(R)-1,3'-Bipyrrolidine Dihydrochloride; (R)-1,3'-Dipyridyl Dihydrochloride (common misnomer); (R)-1,3'-Bipyrrolidine HCl Salt; (R)-1,3'-Bipyrrolidinium Dichloride; (R)-1,3'-Bipyrrolidine Hydrochloride Salt; (R)-1,3'-Bipyrrolidine, 2HCl; (3R)-1,3'-Bipyrrolidine Dihydrochloride; (R)-Bipyrrolidine Dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1,3'-Bipyrrolidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.