Description

7-(4-Chlorobutoxy)-1H-Quinolin-2-One is a high-purity organic chemical intermediate characterized by its quinolin-2-one core functionalized with a chlorobutoxy side chain. This molecular structure makes it a valuable building block for the synthesis of more complex pharmacologically active compounds. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Active Pharmaceutical Ingredient (API) Development: Employed in the synthetic pathway for developing potential APIs, especially within the quinoline derivative class.
• Biochemical Research: May be used as a tool compound in biochemical assays to study enzyme interactions or receptor binding.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	7-(4-Chlorobutoxy)-1H-Quinolin-2-One
CAS No.	913613-82-8
Molecular Formula	C₁₃H₁₄ClNO₂
Molecular Weight	251.71 g/mol
Synonyms	7-(4-Chlorobutoxy)-2(1H)-quinolinone; 7-(4-Chlorobutoxy)quinolin-2(1H)-one; 1H-Quinolin-2-one, 7-(4-chlorobutoxy)-; 913613-82-8; 7-(4-Chlorobutoxy)-1H-quinolin-2-one; 7-(ω-Chlorobutoxy)-2(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our 7-(4-Chlorobutoxy)-1H-Quinolin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure the material meets your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.