Description

Pyrido[2,3-D]Pyrimidine-6-Carbonitrile, 8-(4-Fluorophenyl)-1,4,7,8-Tetrahydro-2-Methyl-4,7-Dioxo-5-Phenyl- (9Ci) is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for developing novel pharmaceutical candidates, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on creating new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological pathways and target validation.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.
• Academic Research: Utilized in university and institutional labs for exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	Pyrido[2,3-D]Pyrimidine-6-Carbonitrile, 8-(4-Fluorophenyl)-1,4,7,8-Tetrahydro-2-Methyl-4,7-Dioxo-5-Phenyl- (9Ci)
CAS No.	912966-13-3
Molecular Formula	C21H15FN4O2
Molecular Weight	374.37 g/mol
Synonyms	8-(4-Fluorophenyl)-1,4,7,8-tetrahydro-2-methyl-4,7-dioxo-5-phenylpyrido[2,3-d]pyrimidine-6-carbonitrile; 5-Phenyl-8-(4-fluorophenyl)-2-methyl-1,4,7,8-tetrahydropyrido[2,3-d]pyrimidine-4,7-dione-6-carbonitrile; Pyrido[2,3-d]pyrimidine-6-carbonitrile, 8-(4-fluorophenyl)-1,4,7,8-tetrahydro-2-methyl-4,7-dioxo-5-phenyl-; 912966-13-3; 8-(4-Fluorophenyl)-2-methyl-4,7-dioxo-5-phenyl-1,4,7,8-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to a quality management system suitable for supplying materials for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.