Description

5-(3-Chloro-4-Methoxy-Phenyl)-Isoxazole-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals. The product is supplied with a focus on consistent quality and reliable supply chain integrity for global R&D and production needs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug molecules, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides, leveraging the isoxazole moiety for biological activity.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• API Development: Employed in the late-stage functionalization and optimization of candidate compounds during preclinical development.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Material Science: Potential use in the development of specialty polymers and functional materials with specific electronic or photonic properties.

Basic Information

Product Name	5-(3-Chloro-4-Methoxy-Phenyl)-Isoxazole-3-Carboxylic Acid
CAS No.	912763-92-9
Molecular Formula	C11H8ClNO4
Molecular Weight	253.64 g/mol
Synonyms	5-(3-Chloro-4-methoxyphenyl)isoxazole-3-carboxylic acid; 3-Isoxazolecarboxylic acid, 5-(3-chloro-4-methoxyphenyl)-; 5-(3-Chloro-4-methoxyphenyl)-1,2-oxazole-3-carboxylic acid; 912763-92-9; AI3-52385; ZINC000000109965; SCHEMBL233468; BCP31834; 5-(3-chloro-4-methoxyphenyl)isoxazole-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of 5-(3-Chloro-4-Methoxy-Phenyl)-Isoxazole-3-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality assurance protocols are designed to meet the exacting standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. We operate under a quality management system and can support customer audits and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.