Description

5-Bromo-6-(cyclopropylmethoxy)nicotinic acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct brominated nicotinic acid core. This compound matters for its critical role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modifications. Pharmaceutical research and development organizations, as well as fine chemical manufacturers, need this material to drive innovation in drug discovery programs targeting a range of diseases.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Drug Discovery & Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies due to its modifiable bromine and carboxylic acid functional groups.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and herbicides.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	5-Bromo-6-(Cyclopropylmethoxy)Nicotinic Acid
CAS No.	912454-38-7
Molecular Formula	C10H10BrNO3
Molecular Weight	272.10 g/mol
Synonyms	5-Bromo-6-(cyclopropylmethoxy)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-bromo-6-(cyclopropylmethoxy)-; 912454-38-7; 5-Bromo-6-cyclopropylmethoxynicotinic acid; Nicotinic acid, 5-bromo-6-(cyclopropylmethoxy)-; 5-Bromo-6-(cyclopropylmethyloxy)nicotinic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-(cyclopropylmethoxy)nicotinic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids and bases. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to minimize exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.