Description

cis-3-Methyl-Tetrahydro-Pyran-4-Ylamine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a rigid, stereodefined scaffold essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research and development chemists and process scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and active ingredient development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the construction of novel, stereospecific herbicides, fungicides, and insecticides where the specific spatial orientation of the molecule is crucial for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity in chemical reactions.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying biological pathways and protein-ligand interactions due to its amine functionality and defined stereochemistry.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	cis-3-Methyl-Tetrahydro-Pyran-4-Ylamine Hydrochloride
CAS No.	911825-81-5
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	cis-3-Methyl-4-aminotetrahydropyran Hydrochloride; (3R,4S)-3-Methyltetrahydro-2H-pyran-4-amine Hydrochloride; (3S,4R)-3-Methyltetrahydro-2H-pyran-4-amine Hydrochloride; 4-Amino-3-methyltetrahydropyran Hydrochloride (cis); 3-Methyl-4-aminotetrahydropyran HCl; THP-Amine Derivative Hydrochloride; 911825-81-5
EINECS	Contact for details

Quality Control

Every batch of cis-3-Methyl-Tetrahydro-Pyran-4-Ylamine Hydrochloride is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including chiral purity verification, is performed. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.