Description

(R)-5,6,7,8-Tetrahydroquinolin-5-Amine is a chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its rigid, fused bicyclic structure and stereogenic center, which are crucial for imparting specific three-dimensional properties to target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals, where precise stereochemistry is a critical design parameter.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in advanced crop protection products.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereochemical configurations.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry and for creating compound libraries for screening.

Basic Information

Product Name	(R)-5,6,7,8-Tetrahydroquinolin-5-Amine
CAS No.	911825-73-5
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(5R)-5,6,7,8-Tetrahydroquinolin-5-amine; (R)-5-Amino-5,6,7,8-tetrahydroquinoline; (R)-5,6,7,8-Tetrahydro-5-quinolinamine; (R)-THQA; (R)-Aminotetrahydroquinoline; (R)-5-Aminotetrahydroquinoline; (R)-5,6,7,8-Tetrahydroquinolin-5-ylamine; (R)-5,6,7,8-Tetrahydro-8-quinolinamine
EINECS	Contact for details

Quality Control

Our (R)-5,6,7,8-Tetrahydroquinolin-5-Amine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.