Description

5,6,7,8-Tetrahydro-2,4-Bis(Trifluoromethyl)-Pyrido[3,4-D]Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure and trifluoromethyl groups. This compound is of significant commercial value for its role in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• CNS Drug Development: Serves as a precursor for compounds targeting neurological pathways and receptors.
• Oncology Research: Employed in the creation of potential kinase inhibitors and other targeted cancer therapies.
• Chemical Biology: Utilized as a probe or tool compound for studying specific enzymatic or cellular processes.
• Process Chemistry: Used in scale-up and route development for the commercial manufacturing of complex drug molecules.

Basic Information

Product Name	5,6,7,8-Tetrahydro-2,4-Bis(Trifluoromethyl)-Pyrido[3,4-D]Pyrimidine Hydrochloride
CAS No.	911636-86-7
Molecular Formula	C10H9ClF6N3
Molecular Weight	320.64 g/mol
Synonyms	2,4-Bis(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride; 5,6,7,8-Tetrahydro-2,4-bis(trifluoromethyl)pyrido[3,4-d]pyrimidine HCl; Pyrido[3,4-d]pyrimidine, 5,6,7,8-tetrahydro-2,4-bis(trifluoromethyl)-, hydrochloride (1:1); 911636-86-7 (CAS); TH-BTPP-HCl
EINECS	Contact for details

Quality Control

Our production of 5,6,7,8-Tetrahydro-2,4-Bis(Trifluoromethyl)-Pyrido[3,4-D]Pyrimidine Hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for research and development. All materials are characterized using advanced analytical techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.