Description

(R)-(+)-1-(4-Methoxyphenyl)Ethylamine-Hcl CAS NO 911373-69-8 is a high-purity chiral amine hydrochloride salt, serving as a critical chiral building block and resolving agent in advanced organic synthesis. Its enantiomeric purity is essential for producing optically active compounds with specific biological activities. This intermediate is primarily utilized by the pharmaceutical, agrochemical, and fine chemical industries for the research and development of active pharmaceutical ingredients (APIs), catalysts, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure APIs, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used to develop chiral ligands for transition metal catalysis, enabling enantioselective transformations like hydrogenation and cross-coupling.
• Chiral Resolving Agent: Employed for the optical resolution of racemic mixtures of carboxylic acids and other acidic compounds.
• Agrochemical Synthesis: Intermediate in the production of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical & Specialty Material Production: Building block for advanced materials, liquid crystals, and specialty polymers requiring chiral centers.
• Academic & Industrial R&D: Serves as a standard reagent in method development and discovery chemistry within research laboratories.

Basic Information

Item	Details
Product Name	(R)-(+)-1-(4-Methoxyphenyl)Ethylamine Hydrochloride
CAS No.	911373-69-8
Molecular Formula	C9H14ClNO
Molecular Weight	187.66 g/mol
Synonyms	(R)-(+)-1-(4-Methoxyphenyl)ethylamine hydrochloride; (R)-1-(4-Methoxyphenyl)ethanamine hydrochloride; (R)-α-Methyl-4-methoxybenzylamine hydrochloride; (R)-4-Methoxy-α-methylbenzylamine HCl; (R)-p-Methoxy-α-methylbenzylamine hydrochloride; (R)-PMBA HCl; (R)-O-Methyl-PEA HCl; (R)-1-(4-Methoxyphenyl)ethylammonium chloride
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-(4-Methoxyphenyl)Ethylamine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) documenting identity, purity, and chiral purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.