Description

Cyclobutanol, 1-(Aminomethyl)-, Hydrochloride (1:1) is a high-purity, functionalized cyclobutane derivative offered as a stable hydrochloride salt. This compound is a critical pharmaceutical intermediate and building block for medicinal chemistry research and advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the unique strained-ring geometry of cyclobutane into novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Building Block: Used in high-throughput screening and combinatorial chemistry to create diverse compound libraries for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a starting material for developing novel herbicides, fungicides, and insecticides with enhanced biological activity.
• Ligand and Catalyst Development: The aminomethyl functionality makes it valuable for creating chiral ligands, organocatalysts, and metal-organic frameworks (MOFs).
• Peptidomimetic Research: The cyclobutane scaffold is used to design conformationally restricted peptide analogs to improve metabolic stability and bioavailability.
• Material Science Precursor: Employed in the synthesis of specialty polymers and advanced materials with tailored thermal or mechanical properties.

Basic Information

Product Name	Cyclobutanol, 1-(Aminomethyl)-, Hydrochloride (1:1)
CAS No.	911060-81-6
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	1-(Aminomethyl)cyclobutanol Hydrochloride; (Aminomethyl)cyclobutanol HCl; 1-(Aminomethyl)cyclobutan-1-ol Hydrochloride; Cyclobutanemethanol, 1-amino-, hydrochloride; 1-Hydroxycyclobutylmethylamine hydrochloride; 1-(Hydroxymethyl)cyclobutylamine hydrochloride
EINECS	Contact for details

Quality Control

Our Cyclobutanol, 1-(Aminomethyl)-, Hydrochloride (1:1) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.