Description

Butanoic Acid, 2-Hydroxy-2-(Trifluoromethyl)-, Hydrazide is a specialized fluorinated hydrazide derivative, a high-value intermediate prized for its unique trifluoromethyl and hydrazide functional groups. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research where fluorine substitution is critical for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting CNS disorders, oncology, and metabolic diseases where the trifluoromethyl group enhances lipophilicity and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms to improve environmental stability and pesticidal activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry, useful for fine chemical and API manufacturing.
• Advanced Material Research: Employed in the development of fluorinated polymers and specialty coatings, where it can impart unique surface properties, chemical resistance, and durability.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes and tags for studying biological pathways and protein interactions in academic and industrial research settings.

Basic Information

Product Name	Butanoic Acid, 2-Hydroxy-2-(Trifluoromethyl)-, Hydrazide
CAS No.	910656-45-0
Molecular Formula	C5H9F3N2O2
Molecular Weight	186.13 g/mol
Synonyms	2-Hydroxy-2-(trifluoromethyl)butyric acid hydrazide; 2-Hydroxy-2-(trifluoromethyl)butanehydrazide; 2-(Trifluoromethyl)-2-hydroxybutyric hydrazide; α-Hydroxy-α-(trifluoromethyl)butyric acid hydrazide; 2-Hydroxy-2-trifluoromethylbutyric acid hydrazide; Butanoic acid, 2-hydroxy-2-(trifluoromethyl)-, hydrazide; 910656-45-0; 2-Hydroxy-2-(trifluoromethyl)butyrohydrazide
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 2-Hydroxy-2-(Trifluoromethyl)-, Hydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports cGMP-compliant workflows for our pharmaceutical and advanced material partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.