Description

2-Aminomethyl-3-(2-Fluoro-Phenyl)-Propionic Acid is a specialized fluorinated amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a carboxylic acid functional group on a fluorinated phenylpropionic acid backbone, makes it a valuable intermediate for creating complex molecules with targeted properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive compounds where the fluorine atom can modulate potency, metabolic stability, and bioavailability.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to incorporate fluorinated phenylalanine analogs into peptides and protein-like structures to enhance their stability and binding affinity.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced herbicides and pesticides, where the fluorine atom can improve efficacy and environmental profile.
• Ligand & Catalyst Development: Employed in the creation of novel chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop fluorescent or affinity tags and other molecular probes for studying biological processes.
• Material Science Research: A potential monomer for synthesizing specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	2-Aminomethyl-3-(2-Fluoro-Phenyl)-Propionic Acid
CAS No.	910443-81-1
Molecular Formula	C11H12FNO2
Molecular Weight	209.22 g/mol
Synonyms	2-(Aminomethyl)-3-(2-fluorophenyl)propanoic acid; 3-(2-Fluorophenyl)-2-(aminomethyl)propanoic acid; β-(Aminomethyl)-2-fluorohydrocinnamic acid; (2-Fluorophenyl)-β-alanine derivative; 2-Fluoro-β-homophenylalanine analog; 2-Aminomethyl-3-(o-fluorophenyl)propionic acid; NSC 760463; Fmoc-2-Aminomethyl-3-(2-Fluoro-Phenyl)-Propionic Acid (protected form)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2-Aminomethyl-3-(2-Fluoro-Phenyl)-Propionic Acid is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.