Description

Catasium(R) Mqf(R)Rh, 1,2-Bis[(2R,5R)-2,5-Dimethyl-Phospholanyl]3,3,4,4-Tetrafluoro-1-Cyclobutene(1,5-Cyclooctadiene)Rhodium(I) Tetrafluoroborate is a highly specialized, chiral rhodium(I) complex featuring a unique fluorinated cyclobutene backbone and dimethylphospholane ligands. This compound matters as a premium, air-stable catalyst precursor designed for high-performance asymmetric hydrogenation and other transition metal-catalyzed reactions. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require exceptional enantioselectivity and catalytic efficiency for synthesizing chiral intermediates.

Application

• Asymmetric Hydrogenation Catalyst: A key precursor for the enantioselective reduction of prochiral olefins, enamines, and ketones in pharmaceutical API synthesis.
• Chiral Ligand Evaluation: Serves as a benchmark complex for studying and developing new chiral phospholane ligand systems in academic and industrial research.
• Fine Chemical Synthesis: Enables the production of high-value, optically pure compounds for fragrances, flavors, and advanced materials.
• Process Chemistry Development: Used in the scale-up and optimization of catalytic routes for agrochemicals and other specialty chemicals.
• Methodology Research: Employed in developing new catalytic protocols for C-H activation, hydroformylation, and other bond-forming reactions.

Basic Information

Product Name	Catasium(R) Mqf(R)Rh, 1,2-Bis[(2R,5R)-2,5-Dimethyl-Phospholanyl]3,3,4,4-Tetrafluoro-1-Cyclobutene(1,5-Cyclooctadiene)Rhodium(I) Tetrafluoroborate
CAS No.	910048-20-3
Molecular Formula	C₂₄H₃₆F₄P₂Rh·BF₄
Molecular Weight	Contact for details
Synonyms	1,2-Bis[(2R,5R)-2,5-Dimethylphospholano]benzene(1,5-cyclooctadiene)rhodium(I) Tetrafluoroborate (with fluorinated backbone); Rhodium(I) (1,2-bis((2R,5R)-2,5-dimethylphospholanyl)-3,3,4,4-tetrafluorocyclobut-1-ene)(1,5-cyclooctadiene) tetrafluoroborate; Mqf(R)Rh BF₄; Catasium MqfRh; DuPhos-type Rhodium Catalyst (fluorinated analog); Chiral Rhodium-DuPhos Complex; [Rh((R,R)-Me-DuPhos)(COD)]BF₄ (fluorinated derivative); Asymmetric Hydrogenation Catalyst Precursor.
EINECS	Contact for details

Quality Control

Every batch of our chiral catalyst precursors is manufactured and tested under strict quality management protocols to ensure consistent high performance. We provide comprehensive Certificates of Analysis (COA) detailing critical parameters such as chiral purity (enantiomeric excess), Rhodium content, and impurity profiles via NMR, HPLC, and elemental analysis. Our quality systems support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere. This material is sensitive to fluoride/strong alkali and should be kept separate from such agents. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	Orange to red crystalline solid or powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Chiral Purity (ee)	≥ 99% (by chiral HPLC or NMR)
Rhodium Content	Contact for details
Solubility	Soluble in dichloromethane, acetone; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.