Description

Dirhodium (II) Tetrakis(Methyl 2-Pyrrolidone-5(R)-Carboxylate)Acetonitrile/2-Propanol Complex is a highly specialized chiral dirhodium(II) carboxylate catalyst. This compound matters for its exceptional ability to facilitate enantioselective carbenoid transformations, including cyclopropanation, C-H insertion, and ylide formation reactions. It is a critical tool for researchers and process chemists in the pharmaceutical and fine chemical industries seeking to construct complex, stereodefined molecular architectures with high precision.

Application

• Asymmetric Synthesis: A premier catalyst for enantioselective intermolecular and intramolecular C-H functionalization reactions.
• Pharmaceutical Intermediates: Enables the synthesis of chiral, biologically active compounds and complex drug candidates.
• Cyclopropanation: Used in the stereocontrolled synthesis of cyclopropane rings, key motifs in many agrochemicals and pharmaceuticals.
• Ylide Formation & Rearrangement: Catalyzes reactions involving carbonyl ylides for the construction of oxygen-containing heterocycles.
• Methodology Development: A valuable reagent for academic and industrial R&D focused on discovering new catalytic asymmetric transformations.
• Fine Chemical Production: Applied in the pilot-scale and commercial manufacture of high-value, optically pure specialty chemicals.

Basic Information

Product Name	Dirhodium (II) Tetrakis(Methyl 2-Pyrrolidone-5(R)-Carboxylate)Acetonitrile/2-Propanol Complex
CAS No.	13796-58-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dirhodium(II) tetrakis[methyl (5R)-2-oxo-5-pyrrolidinecarboxylate] acetonitrile/isopropanol complex; Rh2(5R-MEPY)4•CH3CN•(CH3)2CHOH; Dirhodium(II) tetra((R)-methyl 2-pyrrolidone-5-carboxylate) solvate; (R)-Methyl pyrrolidone-5-carboxylate dirhodium complex; Dirhodium(II) carboxylate catalyst Rh2(R-MPYC)4; Chiral dirhodium catalyst 13796-58-2.
EINECS	Contact for details

Quality Control

Our Dirhodium (II) Tetrakis(Methyl 2-Pyrrolidone-5(R)-Carboxylate)Acetonitrile/2-Propanol Complex is produced and handled under strict quality protocols to ensure batch-to-batch consistency and catalytic performance. Each lot undergoes rigorous analytical testing, including chiral purity and metal content analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific performance characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and maintain stability. Allow the container to reach room temperature in a dry environment before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Green to blue-green solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Chiral Purity	≥ 98% ee
Rhodium Content	~21-23% (Theoretical)
Solvent Content (NMR)	Residual solvents within ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.