Description

Pentafluorophenyl 3-(1-Methyl-1H-Pyrazol-3-Yl)Benzoate is a specialized fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its core value lies in the reactive pentafluorophenyl ester group, which serves as an excellent leaving group for efficient amide and peptide bond formation under mild conditions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry programs and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in fragment-based drug discovery.
• Peptide & Amide Coupling Reagent: Acts as an efficient acylating agent for the preparation of amides and peptides without racemization.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with fluorinated motifs.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced organic materials requiring specific fluorinated aromatic units.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and bioconjugation reagents.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis organizations (CSOs) producing high-value, low-volume specialty chemicals for clients.

Basic Information

Product Name	Pentafluorophenyl 3-(1-Methyl-1H-Pyrazol-3-Yl)Benzoate
CAS No.	910037-11-5
Molecular Formula	C19H11F5N2O2
Molecular Weight	394.30 g/mol
Synonyms	3-(1-Methyl-1H-pyrazol-3-yl)benzoic acid pentafluorophenyl ester; Pentafluorophenyl 3-(1-methyl-1H-pyrazol-3-yl)benzoate; 3-(1-Methylpyrazol-3-yl)benzoic acid 2,3,4,5,6-pentafluorophenyl ester; Benzoic acid, 3-(1-methyl-1H-pyrazol-3-yl)-, 2,3,4,5,6-pentafluorophenyl ester; PFP 3-(1-Methyl-1H-pyrazol-3-yl)benzoate; Pentafluorophenyl ester of 3-(1-methylpyrazol-3-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 3-(1-Methyl-1H-Pyrazol-3-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.