Description

2,2-Dibromo-2,3-Dihydro-5-Fluoro-1H-Inden-1-One is a specialized fluorinated and brominated indanone derivative, serving as a critical advanced intermediate in modern synthetic organic chemistry. Its unique halogenated structure makes it a valuable building block for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This high-purity compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific halogen functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated and brominated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the dibromo-fluoro motif can enhance biological activity and environmental stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a precursor for more complex heterocyclic systems in academic and industrial R&D.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, liquid crystals, or organic electronic materials requiring halogenated aromatic components.
• Chemical Biology Probe Development: Useful for creating tagged molecular probes to study enzyme mechanisms or protein-ligand interactions due to its reactive halogen handles.

Basic Information

Product Name	2,2-Dibromo-2,3-Dihydro-5-Fluoro-1H-Inden-1-One
CAS No.	909806-51-5
Molecular Formula	C9H5Br2FO
Molecular Weight	307.94 g/mol
Synonyms	5-Fluoro-2,2-dibromo-2,3-dihydro-1H-inden-1-one; 2,3-Dihydro-5-fluoro-2,2-dibromo-1H-inden-1-one; 1H-Inden-1-one, 2,2-dibromo-2,3-dihydro-5-fluoro-; 2,2-Dibromo-5-fluoroindan-1-one; 5-Fluoro-2,2-dibromoindan-1-one; DBDFI (abbreviation); Fluorinated Dibromo Indanone
EINECS	Contact for details

Quality Control

Every batch of 2,2-Dibromo-2,3-Dihydro-5-Fluoro-1H-Inden-1-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.