Description

8-Bromo-5-Chloro-1,6-Naphthyridine is a high-purity halogenated naphthyridine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique fused heterocyclic structure, which provides a versatile scaffold for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the naphthyridine core into more complex molecular architectures.
• Academic & R&D: Utilized in university and corporate laboratories for fundamental research on heterocyclic chemistry and reaction mechanism studies.

Basic Information

Product Name	8-Bromo-5-Chloro-1,6-Naphthyridine
CAS No.	909649-12-3
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	8-Bromo-5-chloro-1,6-naphthyridine; 5-Chloro-8-bromo-1,6-naphthyridine; 1,6-Naphthyridine, 8-bromo-5-chloro-; 909649-12-3; 8-Br-5-Cl-1,6-Naphthyridine
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Chloro-1,6-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.