Description

Tetrakis[(R)-(-)-(1-Adamantyl)-(n-Phthalimido)Acetato]Dirhodium(II) Rh2(R-Ptad)4 is a highly specialized chiral dirhodium(II) carboxylate catalyst, recognized for its exceptional enantioselectivity in asymmetric synthesis. This compound is critical for enabling high-value, stereocontrolled chemical transformations that are essential in advanced pharmaceutical and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel, optically pure active ingredients.

Application

• Asymmetric Cyclopropanation: A premier catalyst for the enantioselective synthesis of chiral cyclopropanes, key structural motifs in many bioactive molecules.
• C-H Amination Reactions: Enables the direct, stereoselective insertion of nitrogen into C-H bonds for efficient synthesis of chiral amines and heterocycles.
• Enantioselective Carbonoid Insertions: Facilitates X-H (where X = Si, N, O, S) insertions with high enantiocontrol for building complex molecular architectures.
• Pharmaceutical Intermediate Synthesis: Used in the research and scale-up production of chiral drug candidates, including those for central nervous system (CNS) and antiviral therapies.
• Agrochemical Active Ingredient Development: Applied in creating enantiomerically pure herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Methodology Development in Academic Research: A valuable tool for chemists exploring new asymmetric catalytic cycles and reaction mechanisms.
• Fragrance and Flavor Chemistry: Employed in the synthesis of specific, high-value chiral odorants and flavor compounds.

Basic Information

Item	Detail
Product Name	Tetrakis[(R)-(-)-(1-Adamantyl)-(n-Phthalimido)Acetato]Dirhodium(II)
CAS No.	909393-65-3
Molecular Formula	C84H80N4O12Rh2
Molecular Weight	1548.36 g/mol
Synonyms	Rh2(R-PTAD)4; Dirhodium(II) Tetrakis[(R)-(-)-(1-Adamantyl)-(n-Phthalimido)Acetate]; Rh2(R-ptad)4; (R)-Adamantylphthalimido Dirhodium Catalyst; Chiral Dirhodium(II) Carboxylate Catalyst Rh2(R-PTAD)4; Tetrakis[methyl (1R)-2-(1-adamantyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-1-acetato]dirhodium
EINECS	Contact for details

Quality Control

Every batch of Rh2(R-PTAD)4 is manufactured and analyzed under strict quality protocols to ensure consistent, high catalytic performance. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C in a dry, cool place. Due to its moisture-sensitive and easily oxidized nature, the container should only be opened in a controlled, dry environment and be promptly resealed.

Specification

Item	Specification
Appearance	Dark green to blue-green crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Rhodium Content	12.8 - 13.4 %
Solubility	Soluble in chlorinated solvents (DCM, chloroform), sparingly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.