Description

5,6,7,8-Tetrahydro-2-(1-Piperazinyl)-4(3H)-Quinazolinone is a heterocyclic organic compound featuring a fused quinazolinone and piperazine structure, serving as a key advanced pharmaceutical intermediate. This compound is valued for its role as a versatile synthetic building block in medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for potential therapeutic compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	5,6,7,8-Tetrahydro-2-(1-Piperazinyl)-4(3H)-Quinazolinone
CAS No.	909299-09-8
Molecular Formula	C12H16N4O
Molecular Weight	232.28 g/mol
Synonyms	2-(Piperazin-1-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one; 5,6,7,8-Tetrahydro-2-(piperazin-1-yl)quinazolin-4(3H)-one; THPQ; 909299-09-8; Tetrahydroquinazolinone piperazine derivative; 4(3H)-Quinazolinone, 5,6,7,8-tetrahydro-2-(1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-2-(1-Piperazinyl)-4(3H)-Quinazolinone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and intermediate use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.