Description

(2R,3R)-2-(4-Bromophenyl)-3-(Perfluorophenyl)Oxirane is a high-purity, chiral epoxide building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a brominated aromatic ring with a perfluorinated aromatic system, enabling precise stereochemical control and introducing distinct electronic properties into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in developing novel herbicides and pesticides with enhanced activity and environmental profile, leveraging the stability of the perfluorophenyl group.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for advanced electronic materials, where the combination of bromo and perfluoro substituents can fine-tune molecular polarity and packing.
• Asymmetric Catalysis Substrate: Employed in methodological studies to develop and test new chiral catalysts for ring-opening reactions of epoxides.
• Polymer Functionalization: Used to introduce reactive epoxide and aromatic halogen functionalities into polymer backbones for creating specialty resins and coatings.
• Chemical Biology Probe Development: Acts as a versatile handle for bioconjugation and labeling strategies in probe and tool compound synthesis.

Basic Information

Product Name	(2R,3R)-2-(4-Bromophenyl)-3-(Perfluorophenyl)Oxirane
CAS No.	908838-33-5
Molecular Formula	C14H6BrF5O
Molecular Weight	377.10 g/mol
Synonyms	(2R,3R)-2-(4-Bromophenyl)-3-(Pentafluorophenyl)oxirane; (2R,3R)-2-(p-Bromophenyl)-3-(perfluorophenyl)oxirane; (2R,3R)-rel-2-(4-Bromophenyl)-3-(2,3,4,5,6-pentafluorophenyl)oxirane; (2R,3R)-2-(4-Bromophenyl)-3-(2,3,4,5,6-pentafluorophenyl)oxirane; (2R,3R)-2-(4-Bromophenyl)-3-(C6F5)Oxirane; Chiral Bromo-Perfluorophenyl Epoxide; (2R,3R)-Bromo-Pentafluorophenyl Oxirane
EINECS	Contact for details

Quality Control

Our (2R,3R)-2-(4-Bromophenyl)-3-(Perfluorophenyl)Oxirane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.