Description

3-(1-(tert-Butoxycarbonyl)Piperidin-3-Yl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a benzoic acid moiety linked to a tert-butoxycarbonyl (Boc)-protected piperidine ring. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting neurological and metabolic disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, where its role as a key building block enables precise molecular construction and functionalization.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel drug candidates, especially for central nervous system (CNS) and GPCR-targeted therapies.
• Protease Inhibitor Research: Used in the development and optimization of protease inhibitors, where the piperidine scaffold is a common pharmacophore.
• Peptidomimetic Chemistry: Employed to introduce constrained, chiral amino acid analogs into peptide chains to enhance stability and bioavailability.
• Chemical Biology Probes: Acts as a starting material for creating labeled compounds or affinity probes for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials under cGMP guidelines.
• Academic & Industrial R&D: Utilized in exploratory research for constructing diverse compound libraries via parallel and combinatorial synthesis.

Basic Information

Product Name	3-(1-(tert-Butoxycarbonyl)Piperidin-3-Yl)Benzoic Acid
CAS No.	908334-19-0
Molecular Formula	C17H23NO4
Molecular Weight	305.37 g/mol
Synonyms	3-(1-Boc-piperidin-3-yl)benzoic acid; 3-(1-((tert-Butoxy)carbonyl)piperidin-3-yl)benzoic acid; 3-(1-(tert-Butoxycarbonyl)-3-piperidyl)benzoic acid; 3-(N-Boc-3-piperidyl)benzoic acid; Benzoic acid, 3-[1-[(1,1-dimethylethoxy)carbonyl]-3-piperidinyl]-; 3-(1-Boc-3-piperidyl)benzoic acid; 3-(Piperidin-3-yl)benzoic acid tert-butyl carbamate; BOC-3-Piperidylbenzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-(1-(tert-Butoxycarbonyl)Piperidin-3-Yl)Benzoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.