Description

1H-Indene-2-Carboxylic Acid, 2-Amino-5-Bromo-2,3-Dihydro-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex, functionalized indene core structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. Pharmaceutical R&D and fine chemical synthesis companies need this material to develop next-generation therapeutic candidates, leveraging its unique bromo and amino substituents for precise molecular construction.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug molecules, especially in medicinal chemistry research.
• Organic Synthesis Building Block: Utilized in coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyclization processes to construct polycyclic frameworks.
• Research & Development: Essential for academic and industrial laboratories exploring new chemical entities (NCEs) and structure-activity relationships (SAR).
• Agrochemical Synthesis: Potential intermediate for developing novel crop protection agents with specific biological activity.
• Material Science Precursor: Can be investigated for the synthesis of organic semiconductors or specialty polymers with tailored electronic properties.

Basic Information

Product Name	1H-Indene-2-Carboxylic Acid, 2-Amino-5-Bromo-2,3-Dihydro-, Ethyl Ester
CAS No.	907944-96-1
Molecular Formula	C₁₂H₁₂BrNO₂
Molecular Weight	282.13 g/mol
Synonyms	Ethyl 2-Amino-5-bromo-2,3-dihydro-1H-indene-2-carboxylate; 2-Amino-5-bromo-2,3-dihydro-1H-indene-2-carboxylic acid ethyl ester; 5-Bromo-2-aminoindane-2-carboxylic acid ethyl ester; 907944-96-1; AI3-52345; SCHEMBL23346877; ZINC000253899996; AKOS040759232
EINECS	Contact for details

Quality Control

Our 1H-Indene-2-Carboxylic Acid, 2-Amino-5-Bromo-2,3-Dihydro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.