Description

3,5-Dimethy-L-Phenylalanine Hydrochloride is a high-purity, non-natural amino acid derivative used as a critical chiral building block in advanced organic synthesis. Its value lies in providing a sterically hindered, enantiomerically pure phenylalanine core for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel peptide-based therapeutics, enzyme inhibitors, and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel active pharmaceutical ingredients (APIs), especially in peptide and peptidomimetic drug discovery.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a dimethyl-substituted phenylalanine residue, influencing the peptide's conformation, stability, and receptor binding affinity.
• Protease & Enzyme Inhibitor Development: Serves as a core structure in designing potent and selective inhibitors for various enzymes, leveraging its modified aromatic side chain.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and labeled peptides for studying enzyme function and protein-protein interactions.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for synthesizing chiral ligands and catalysts used in enantioselective transformations.
• Material Science: Potential use in creating functionalized polymers and advanced materials with specific chiral properties.

Basic Information

Product Name	3,5-Dimethy-L-Phenylalanine Hydrochloride
CAS No.	906365-71-7
Molecular Formula	C11H16ClNO2
Molecular Weight	229.70 g/mol
Synonyms	L-3,5-Dimethylphenylalanine hydrochloride; (2S)-2-Amino-3-(3,5-dimethylphenyl)propanoic acid hydrochloride; 3,5-Dimethyl-DL-phenylalanine hydrochloride (racemic mixture); H-3,5-Dimethyl-Phe-OH.HCl; Fmoc-3,5-dimethyl-L-phenylalanine (precursor); 3,5-Dimethylphenylalanine HCl; 3,5-Dimethyl-L-homophenylalanine hydrochloride
EINECS	Contact for details

Quality Control

Our 3,5-Dimethy-L-Phenylalanine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and cGMP applications. A Certificate of Analysis (COA) detailing specific results for chiral purity, assay, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.