Description

4-((3-Ethynylphenyl)Amino)-7-Methoxyquinazolin-6-Yl Acetate is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel oncology and anti-inflammatory treatments. The material is supplied with stringent quality control to ensure batch-to-batch consistency for critical research and production processes.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of small molecule kinase inhibitors for targeted cancer therapy.
• Oncology Drug Discovery: Used in research and development (R&D) for creating novel compounds that target specific signaling pathways in cancer cells.
• Biochemical Research: Serves as a reference standard or a probe molecule in enzymatic assays and pharmacological studies.
• API Synthesis: Employed in the production of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trial material.
• Chemical Biology: Utilized in the development of chemical tools to study protein function and cellular processes.

Basic Information

Product Name	4-((3-Ethynylphenyl)Amino)-7-Methoxyquinazolin-6-Yl Acetate
CAS No.	905306-07-2
Molecular Formula	C19H15N3O3
Molecular Weight	333.34 g/mol
Synonyms	4-[(3-Ethynylphenyl)amino]-7-methoxy-6-quinazolinyl acetate; 7-Methoxy-4-((3-ethynylphenyl)amino)quinazolin-6-yl acetate; 6-Acetoxy-4-((3-ethynylphenyl)amino)-7-methoxyquinazoline; 905306-07-2; 4-(3-Ethynylanilino)-7-methoxyquinazolin-6-yl acetate
EINECS	Contact for details

Quality Control

Our 4-((3-Ethynylphenyl)Amino)-7-Methoxyquinazolin-6-Yl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container is opened.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.