Description

3-Amino-n-(tert-Butyl)-2-Methylbenzamide is a high-purity, specialized benzamide derivative serving as a critical building block in advanced organic synthesis. Its unique sterically hindered tert-butyl amide group adjacent to an amino functionality makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring steric modification for metabolic stability.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides where the tert-butyl amide group can influence bioavailability and environmental persistence.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce amino-functionalized aromatic units into polymer backbones, altering material properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Fine Chemical Synthesis: Acts as a versatile intermediate for producing other high-value, custom-synthesized specialty chemicals.

Basic Information

Product Name	3-Amino-n-(tert-Butyl)-2-Methylbenzamide
CAS No.	905234-93-7
Molecular Formula	C12H18N2O
Molecular Weight	206.29 g/mol
Synonyms	3-Amino-N-tert-butyl-2-methylbenzamide; 2-Methyl-3-amino-N-(tert-butyl)benzamide; N-(tert-Butyl)-3-amino-2-methylbenzamide; 3-Amino-2-methyl-N-(1,1-dimethylethyl)benzamide; Benzamide, 3-amino-N-(1,1-dimethylethyl)-2-methyl-; 905234-93-7; tert-Butyl (3-amino-2-methylbenzoyl)carbamate derivative
EINECS	Contact for details

Quality Control

Our 3-Amino-n-(tert-Butyl)-2-Methylbenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to ensure consistent quality and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.