Description

3-Bromo-6,7-dihydro-8(5H)-quinolinone is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core quinolinone scaffold, functionalized with a bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, ligands for catalysts, and specialty polymers due to its electron-rich quinolinone core.
• Chemical Synthesis: The bromine atom provides a handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Heck) for library synthesis in medicinal chemistry.
• Academic & Contract Research: Employed in universities and CROs for fundamental research on heterocyclic chemistry and reaction mechanism studies.

Basic Information

Product Name	3-Bromo-6,7-dihydro-8(5H)-quinolinone
CAS No.	904929-24-4
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	3-Bromo-5,6,7,8-tetrahydroquinolin-8-one; 3-Bromo-8-oxo-5,6,7,8-tetrahydroquinoline; 8(5H)-Quinolinone, 3-bromo-6,7-dihydro-; 3-Bromotetrahydroquinolin-8-one
EINECS	Contact for details

Quality Control

Our 3-Bromo-6,7-dihydro-8(5H)-quinolinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.