Description

8-Bromoquinoline-2-Carbaldehyde is a versatile brominated quinoline derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its value lies in the reactive aldehyde and bromine functional groups, which allow for selective cross-coupling and further functionalization to construct complex heterocyclic systems. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active quinoline-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a building block for creating organic ligands in catalysis and for synthesizing advanced organic electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for nucleophilic addition to the aldehyde group.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and for exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	8-Bromoquinoline-2-Carbaldehyde
CAS No.	904886-25-5
Molecular Formula	C10H6BrNO
Molecular Weight	236.07 g/mol
Synonyms	8-Bromo-2-quinolinecarboxaldehyde; 2-Quinolinecarboxaldehyde, 8-bromo-; 8-Bromoquinoline-2-carboxaldehyde; 8-Bromo-2-formylquinoline; 8-Bromoquinaldine-2-carbaldehyde; 904886-25-5; 8-Bromoquinoline-2-aldehyde
EINECS	Contact for details

Quality Control

Our 8-Bromoquinoline-2-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality management system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.