Description

2-(2-tert-Butoxycarbonylamino-Ethylamino)-Nicotinic Acid CAS NO 904815-14-1 is a high-purity, advanced pharmaceutical intermediate featuring a nicotinic acid core protected by a tert-butoxycarbonyl (Boc) group. This compound is critical for the synthesis of complex molecules, offering a protected amine functionality essential for peptide coupling and multi-step organic synthesis. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and neurology research.
• Peptide Synthesis: Serves as a protected amino acid derivative for the controlled assembly of peptide chains in solid-phase and solution-phase synthesis.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
• Protecting Group Chemistry: The Boc group provides a stable, orthogonal protecting strategy for amines during complex multi-step syntheses.
• Ligand and Catalyst Preparation: Can be utilized to create specialized ligands for metal catalysis or as a precursor for functionalized materials.

Basic Information

Product Name	2-(2-tert-Butoxycarbonylamino-Ethylamino)-Nicotinic Acid
CAS No.	904815-14-1
Molecular Formula	C13H19N3O4
Molecular Weight	281.31 g/mol
Synonyms	2-[[2-[(tert-Butoxycarbonyl)amino]ethyl]amino]nicotinic acid; 2-(2-Boc-aminoethylamino)nicotinic acid; Nicotinic acid, 2-[[2-[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]-; 2-(2-(tert-Butoxycarbonylamino)ethylamino)pyridine-3-carboxylic acid; Boc-AEA-Nicotinic Acid; 904815-14-1
EINECS	Contact for details

Quality Control

Our production of 2-(2-tert-Butoxycarbonylamino-Ethylamino)-Nicotinic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled with appropriate precautions for chemicals soluble in strong acid/organic solvent. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.