Description

4-(4-{[(tert-Butoxy)Carbonyl]Amino}Phenyl)-2,4-Dioxobutanoic Acid is a high-purity, protected amino acid derivative featuring a reactive 1,3-diketone moiety. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific enzymatic pathways.
• Peptidomimetic Synthesis: Used to incorporate non-natural amino acid structures into peptide chains to enhance stability, bioavailability, and biological activity.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors of proteolytic enzymes, relevant in antiviral and anticancer drug discovery.
• Chemical Biology Probes: Employed in the creation of activity-based probes (ABPs) for studying enzyme function and target engagement within biological systems.
• Ligand Synthesis for Metal Complexation: The β-diketone functionality allows for chelation with various metal ions, useful in catalysis and materials science.
• Cross-Coupling & Conjugation Chemistry: Acts as a handle for further functionalization via its carboxylic acid group, enabling conjugation to other molecules or solid supports.

Basic Information

Product Name	4-(4-{[(tert-Butoxy)Carbonyl]Amino}Phenyl)-2,4-Dioxobutanoic Acid
CAS No.	904814-16-0
Molecular Formula	C15H17NO6
Molecular Weight	307.30 g/mol
Synonyms	4-(4-((tert-Butoxycarbonyl)amino)phenyl)-2,4-dioxobutanoic acid; 4-(4-{[(tert-Butoxy)carbonyl]amino}phenyl)-2,4-dioxobutanoic acid; 2,4-Dioxo-4-[4-[[(2-methyl-2-propanyl)oxy]carbonyl]amino]phenyl]butanoic acid; Boc-Amino Phenyl Dioxobutanoic Acid; N-Boc-4-amino-β-oxobenzeneacetic acid; 4-(4-(Boc-amino)phenyl)-2,4-dioxobutanoic acid; tert-Butyl (4-(3-carboxy-3-oxopropanoyl)phenyl)carbamate
EINECS	Contact for details

Quality Control

Our 4-(4-{[(tert-Butoxy)Carbonyl]Amino}Phenyl)-2,4-Dioxobutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.